Dementia studies

New NIHR supported research shows that brain health in people over 50 deteriorated more rapidly during the pandemic. This was true regardless of whether they had COVID-19. Researchers analysed brain function tests completed by more than 3,000 UK people aged 50 to 90, many of which were recruited through Join Dementia Research. The results The […]

A new drug has been hailed as a scientific breakthrough in treating Alzheimer’s disease, following the publication of final trial results in the medical journal, JAMA.  The findings show donanemab can successfully slow down decline in memory and thinking by 35 per cent among people with early-stage Alzheimer’s Disease. The drug’s ability to slow down […]

A clinical trial has revealed a new Alzheimer’s drug can successfully slow down decline in memory and thinking by 35 per cent. Donanemab has been shown to significantly reduce cognitive decline in people with early-stage Alzheimer’s disease. The trial by US pharmaceutical company Eli Lilly showed it has been successful in removing sticky amyloid plaques […]

New research has revealed that 91 per cent of people would take a simple test to learn about their risk of developing a brain disease. The anonymous online study, ‘The Global Brain Health Survey’, involved more than 27,500 people worldwide and was led by the Norwegian Institute of Public Health in collaboration with the University […]

A new study in Nottinghamshire is seeking volunteers to form a singing group to study the benefits of singing for people with dementia.  University of Nottingham researchers are seeking 80 people with dementia and their carers to take part in the Preliminary Randomised Evaluation of Singing in Dementia (PRESIDE 2024) study, which is using Join […]

A research study exploring the impact specialist anti-inflammatory drugs have on Alzheimer’s disease symptoms is looking for volunteers in London, Plymouth, Guildford and Southampton. The EXploratory PLatform trial on Anti-INflammatory agents in Alzheimer’s Disease, or EXPLAIN-AD for short, will be evaluating the effectiveness and safety of anti-inflammatory agents on common Alzheimer’s symptoms – including memory, […]

Clinical trials across England and Scotland are underway to investigate if an existing diabetes medicine can potentially work as a disease-modifying option for early-stage Alzheimer’s disease. Novo Nordisk is now working alongside Join Dementia Research to investigate if the medicine, known as semaglutide, could also benefit people living with early Alzheimer’s disease. What the study […]

A national research study is investigating whether a readily available anti-sickness drug could treat dementia-related hallucinations. The Trial of Ondansetron as a Parkinson’s HAllucinations Treatment, or TOP HAT study, is recruiting volunteers across England, Scotland and Wales to evaluate whether ondansetron, an anti-sickness drug used in the NHS, could also be used for treating hallucinations […]

A pioneering international study is exploring how health promotion and self-management programmes could be used to support people with early-stage dementia and improve their health outcomes. The Self-management and HeAlth Promotion in early-stage dementia with E-learning for carers study, or SHAPE for short, is looking to recruit people with a mild to moderate dementia diagnosis […]

There are almost one million people with dementia in the UK and the most common cause is Alzheimer’s disease. Researchers from University College London (UCL) with funding from the National Institute for Health and Care Research are testing a new approach to the treatment of mild Alzheimer’s disease in the DESPIAD (DEpletion of SaP in […]