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Dementia fears for former footballers

25 October 2019

Football on grass

A recent study has found that the risk of dying from neurodegenerative disease is almost 3.5 times higher for footballers. However research is at an early stage and there’s currently no suggestion that anyone should stop playing football. Regular physical activity – including football – is a good way to reduce the risk of dementia and conditions such as heart disease.

In the news: Potential new drug may slow Alzheimer’s disease

23 October 2019

MRI brain scan images

US pharmaceutical company Biogen has announced that they plan to ask US drug regulators to approve their experimental Alzheimer’s drug, aducanumab. Aducanumab is designed to target amyloid, a protein that builds up in the brains of people with the early stages of Alzheimer’s disease. The announcement follows Phase III clinical trials called ENGAGE and EMERGE. New analysis of trial data has produced promising results – those who received high doses of aducanumab showed significant slowing in the decline of their cognitive ability.

Electromagnetic ‘bathing cap’ shows promise in early Alzheimer’s disease trial

23 September 2019

Female research participant wearing the MemorEM electromagnetic skullcap

In a new study, researchers designed a bathing cap-style head device, called the MemorEM, which was used to deliver electromagnetic waves to the brain. The purpose of this was to try to dissolve what are known as oligomers – groups of abnormal proteins – as they were forming. There was some sign of improvements on tests of thinking and memory in most of the people taking part in the study. This is an experimental, early-stage study that looked primarily at safety, so it cannot tell us for sure if the treatment works.

New type of dementia discovered

2 May 2019

Art designed to look like the human brain

Researchers have identified a new form of dementia. Known as LATE, it shares many similarities with Alzheimer’s disease, but tends to lead to a more gradual decline in memory. LATE (limbic-predominant age-related TDP-43 encephalopathy) appears to be linked to the accumulation of a protein called TDP-43 in the brain, whereas Alzheimer’s is linked to the […]

Gum disease linked to Alzheimer’s, study claims

28 January 2019

False teeth with donuts and cakes

This article has been reproduced from the NHS website. “Gum disease bug could play ‘central role’ in development of Alzheimer’s,” The Independent reports. The causes of Alzheimer’s disease are still debated. Most scientists think it is likely to be down to a combination of factors, including your genes and lifestyle. But some believe it may be […]

‘Exercise hormone’ may play a role in combating Alzheimer’s disease

14 January 2019

Dumbbells

This article has been reproduced from the NHS website. “An ‘exercise pill’ mimicking the effects of a gym workout could prevent Alzheimer’s disease,” the Daily Mirror reports. The “pill” is actually a reference to a protein called irisin. Irisin has been dubbed the “exercise hormone” because previous research found it’s released from muscles in response to […]

What’s that study? The Generation Program

26 November 2018

Generation Program logo

We caught up with Professor Lefkos Middleton from Imperial College London, who is UK Chief Investigator for the Generation Program. The Generation Program is a collaboration between Novartis, Amgen and Banner Alzheimer’s Institute, and consists of two clinical trials that may be able to delay the onset of Alzheimer’s disease – Generation Study 1 and […]

Landmark trial for novel Alzheimer’s disease treatment

9 October 2018

Professor Martin Rossor, NIHR National Director for Dementia Research

This story was first published on the NIHR website. The first clinical trial of a completely novel and unprecedented approach to modifying the progression of Alzheimer’s disease has opened at the NIHR University College London Hospitals (UCLH) Clinical Research Facility. The Depletion of serum amyloid P component in Alzheimer’s disease (DESPIAD) trial will test whether […]

Claims of a ‘breakthrough’ for Alzheimer’s patients lack merit

25 June 2018

NHS Choices logo

This article has been reproduced from the NHS Choices website. “Is this the solution to Alzheimer’s?” asks the Mail Online. Sadly, the headline is an overblown reaction to a small, poor-quality and arguably overhyped study. Researchers tested 2 mixtures of nutritional supplements on 25 patients with Alzheimer’s disease. There was no comparison group taking a placebo […]

Proud to help future generations: Carol’s story

15 June 2018

Carol and Bryan Simcock in the garden

A grandmother living with mild Alzheimer’s disease in Greater Manchester is proud to be taking part in clinical research to help future generations. Carol Simcock, 71, lives in Handforth, Cheshire, with her husband Bryan, 78. Carol’s dementia experience Up until her retirement, Carol, a mum-of-two and grandmother-of-two, worked as a secretary and later as a […]

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