The ‘AMPLE’ Study
26 February 2016
The ‘AMPLE’ study, which is based at the University of Newcastle upon Tyne, investigates ‘amyloid imaging’ for the observable characteristics of Dementia with Lewy Bodies (DLB), which is the second most common cause of degenerative dementia in the UK. Beta-amyloid is a protein, deposits of which can be found in the brain of a person who has Alzheimer’s Disease. Until recently, […]
‘Deep and Frequent Phenotyping’
The ‘Deep and Frequent Phenotyping’ Study hopes to produce new ways of diagnosing dementia before symptoms even arise. Aims of the Study We urgently need new and better treatments that can be given to patients as early as possible to prevent brain damage associated with dementia. Researchers want to do studies before brain damage has progressed […]
The Gantenerumab Trial
This study looks at an exciting opportunity to get involved in testing new medication for people with Alzheimer’s Disease. Aims of the Study Alzheimer’s disease is a major global public health problem, and there are nearly 30 million people with the disease worldwide. Alzheimer’s disease is an irreversible, progressive neurodegenerative disease which causes a gradual […]
How can people with dementia be supported and treated in an acceptable way that is affordable?
16 December 2015
A new study to join Join Dementia Research is the MODEM: Comprehensive approach to modelling outcome and cost impacts of interventions for dementia study. It is one part of a larger MODEM project that will generate new evidence to help decision makers in the health and social care sectors to develop and implement strategies to […]
New Alzheimer’s disease drug trial opens across Scotland
24 November 2015
People with Alzheimer’s disease who live in Scotland are being asked to consider taking part in the ground-breaking government-funded RADAR trial. The trial is investigating if a drug normally used to treat high blood pressure (hypertension) has additional properties that could slow down the progression of Alzheimer’s disease (AD) in people with and without hypertension. […]
Can heart scans support diagnosing Dementia with Lewy Bodies?
13 November 2015
Dementia with Lewy bodies (DLB) affects over 100,000 people in the UK, however it is difficult to recognise in clinical practice, with many cases currently undetected. It can also be difficult to distinguish DLB from Alzheimer’s disease. Previous research studies have found that nerve damage can be detected in the hearts of people with DLB, with no such damage observed […]
Can observing computer use help detect memory problems in people over 65?
7 October 2015
The Software Architecture for Mental Health Self-Management (SAMS) Reliability study, based at the University of Manchester, is looking at whether personal computer use, such as emailing and web browsing, can help detect memory or cognitive problems. The study takes place in the participant’s own home and involves some cognitive assessments with a researcher as well as […]
Looking at the relationship between memory disorders and inflammation of the brain
9 September 2015
The Neuroimaging of Inflammation in MemoRy and Other Disorders (NIMROD) study is looking at the relationship between memory disorders and inflammation of the brain. Recent technical developments allow the use of brain imaging methods (Positron Emission Tomography or PET scans) together with marked chemicals to visualise sites of inflammation. Other forms of PET imaging can also […]
Could new drug slow down deterioration of the brain?
18 August 2015
The AMARANTH STUDY will test whether the experimental drug, AZD3293 [LY3314814], slows the worsening of Alzheimer’s disease, compared to a placebo given to patients with Mild Cognitive Impairment (MCI) or Early Alzheimer’s disease. It’s for people aged between 55-85 and is being conducted at several places across the UK, as well as worldwide, to find out if this […]
Phenomenon of selective forgetting in people with dementia
12 August 2015
The Mnemic Neglect in Dementia study, organised by researchers at the University of the West of England, is funded by the Alzheimer’s Society to find out how people react when they are told they have dementia. This study will look at what factors play a role in how people cope with being given a diagnosis of dementia. We […]