Today is World Alzheimer’s Day, so we thought we’d bring you a round-up of just a few of the latest studies investigating Alzheimer’s disease that are looking for volunteers:

 

The MINDSET Study

This drug study, sponsored by Axovant Sciences Ltd., is looking at whether an innovatory new drug could be used to help improve the everyday lives of people with mild-to-moderate Alzheimer’s disease.

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The study will look at whether a drug known as ‘RVT 101’ improves Alzheimer’s patients’ cognition and ability to perform daily living activities when taken together with another drug called ‘donepezil’ (sometimes known as Aricept®).

 
For volunteers, this piece of research will consist of 9 separate visits over a 33 week period and is taking place at a number of sites throughout the UK. Participants who complete the study will then have the opportunity to enrol in a 12-month extension study.

 
Discover more about the MINDSET study.

 

The TASKED Study

Professor Eneida Mioshi, Chief Investigator for the TASKED Study

Professor Eneida Mioshi, Chief Investigator for the TASKED Study

The TASKED study is looking at how factors such as changes to the home environment and the role of carers can help to improve the quality of life for people with dementia.

 
The main part of the study involves completing some questionnaires on everyday activity performance, well-being, carer managing strategies, and some questions on the person with dementia’s memory and cognition. A second part of the study involves direct observations of the person with dementia’s ability to perform everyday activities.

 
The first part of the study will take place in the person with dementia’s and their carer’s home whilst the second part of the study will take place in the participant’s home, as well as on University of East Anglia premises.

 
Find out more about the TASKED study, and see if you’re eligible to take part.

 

Demotivation in Dementia: Development and Validation of a New Scale

Dr Ratko Radakovic, Chief Investigator of this study

Dr Ratko Radakovic, Chief Investigator of this study

This study is looking to explore the different types of demotivation or apathy in people with Alzheimer’s.

 
Demotivation, or apathy, is commonly observed in many different neurodegenerative diseases. It is defined by a lack of motivation that can be seen in all aspects of an individual’s functioning. The researchers in this study is looking to explore different types of apathy and demotivation in people living with Alzheimer’s disease.

 
The study is a one-off, postal questionnaire that takes no longer than 20 minutes to complete. Researchers are looking for people in Scotland with a diagnosis of very mild to moderate Alzheimer disease without marked cognitive impairment.

 
Read more about the Demotivation in Dementia: Development and Validation of a New Scale Study.

 

The ‘EARLY’ Study

This trial is looking at brain protein fragments called ‘Amyloid-beta’ which are sometimes linked with nerve damage. These protein fragments are thought to be an important early marker, or ‘biomarkers’ for Alzheimer’s disease.

 
The main aim of this study is to find out if treatment with a new study drug, when compared to placebo, slows down cognitive decline by reducing the amount of amyloid-beta fragments in the brains of currently healthy volunteers.

 

Dr Stephen Pearson, Chief Investigator for the EARLY Study (UK branch)

Dr Stephen Pearson, Chief Investigator for the EARLY Study (UK branch)

The EARLY study is an international trial, and has nine participating research centres located in the UK, and is looking for volunteers without a diagnosis of dementia to help find out more about the initial causes of Alzheimer’s disease.

 
Find out more about the EARLY Study.